C$56 Cheap Flights from Chicago (CHIA) to Knoxville (TYS)

Compare Chicago to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Chicago to Knoxville

Looking for a cheap last-minute deal or the best return flight from Chicago to Knoxville Airport? If you want to travel next month, return fares start from C$136. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Chicago to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago to Knoxville flights are currently cheapest in November.

Which airlines fly from Chicago to Knoxville?

Chicago to Knoxville: Alternative routes

Compare routes from Chicago to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Chicago to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundC$56
Cheapest month to flyNovember
Average flight time1 hr, 39 mins
Most popular airlineAmerican Airlines
Average flights per week592

Finding cheap flights from Chicago to Knoxville: Frequently asked questions

The best price we found for a return flight from Chicago to Knoxville is C$121. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 39 minutes is the average flight time from Chicago to Knoxville.
American Airlines, United and SkyWest Airlines fly direct from Chicago to Knoxville.
As of May 2026, there are 592 flights per week flying from Chicago to Knoxville.
The cheapest month to fly from Chicago to Knoxville is usually May.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Knoxville Airport on Sunday, May 24, 2026.
Yes – the average flight time is 1 hour and 39 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Knoxville is Allegiant Air .

Flying from Chicago to McGhee Tyson Airport (TYS): what you need to know

  • Start planning your vacation by checking out the most convenient departure point for your flight from Chicago to McGhee Tyson Airport (TYS). Explore the options for taking off from O'Hare International Airport (ORD) or Chicago Midway International Airport (MDW), two of the city's main airports.

  • Take a direct flight from Chicago to McGhee Tyson Airport and you'll be in the air for around 1 hour 44 minutes.

  • McGhee Tyson Airport is located in Knoxville. The city operates in the UTC-4 timezone and is 1 hour ahead of Chicago.

  • The most popular route is from O'Hare International Airport (ORD) to McGhee Tyson Airport (TYS), with 71 direct weekly services. If you'd like to head off as soon as possible, the earliest flight from ORD to TYS is the 07:10 United service. If you have other commitments or plans on your day of travel, the final departure is at 21:14 with Allegiant Air.

  • Give yourself enough time to catch your flight from Chicago to TYS. As a rule of thumb, arrive two hours before international departures and an hour ahead for domestic flights.

  • Popular months like August or vacation times such as spring break and Christmas will mean longer queues at check-in and security. Play it safe and head to the terminal even earlier. Arriving two hours before domestic flights and up four hours ahead of international flights is a wise move.

Airports in Chicago

O'Hare International Airport (ORD)

  • Get there in one go from O'Hare International Airport (ORD). Direct flights from Chicago to McGhee Tyson Airport (TYS) operate from here.

  • You can get away on a direct flight from Chicago to McGhee Tyson Airport with United. This popular airline operates departures from ORD.

  • The distance from central Chicago to ORD is roughly 40 kilometres. Check out Google Maps for the fastest way to get there, whether you plan to drive or take public transport.

  • Need a convenient hotel close to O'Hare International Airport? If you're catching an early flight from Chicago to McGhee Tyson Airport, these stays will have you sleeping moments from check-in:

Chicago Midway International Airport (MDW)

About McGhee Tyson Airport (TYS)

Getting from McGhee Tyson Airport (TYS) to central Knoxville

  • From McGhee Tyson Airport, Knoxville is approximately 23 kilometres away. It takes around 19 minutes to get to the centre driving.

How to find the cheapest flights from Chicago to McGhee Tyson Airport (TYS)

  • The best price we've seen for a one-way ticket from Chicago to McGhee Tyson Airport is C$56. The cheapest price for a return flight is C$121. Keep in mind fares can change due to demand at the time of booking.

  • 8 months is how far you'll want to book ahead to lock in flight tickets from Chicago to TYS.

  • To score the lowest price on your tickets from Chicago to McGhee Tyson Airport, book your trip for May (it's when flights are cheapest). Got flexible travel dates? Use the 'Whole month' search function to see the most affordable day to fly.

  • Create a Price Alert and track any changes on this route through email or push notifications. We'll let you know when fares go down. Timing is key for finding flight tickets from Chicago to TYS.

  • Customize your trip using filters. Adjust the number of stops, total duration, and departure and arrival times to find the right flight from Chicago to McGhee Tyson Airport. You can also sort the results to see the 'Best,' 'Fastest' or 'Cheapest' options first.

The best time to fly from Chicago to McGhee Tyson Airport (TYS)

  • February is the quietest time to fly to Knoxville. Alternatively, join the crowds and visit in July. This is the busiest month for flights from Chicago to McGhee Tyson Airport, but the best time to go is your call.

  • When booking your flight from Chicago to TYS, think about the type of weather you enjoy. July is the warmest month in Knoxville, with the temperature ranging from 17ºC to 32ºC.

  • If you want to travel in cooler conditions, search for a cheap flight from Chicago to McGhee Tyson Airport in January when temperatures average between -6ºC and 11ºC.

More about Knoxville

Complete your Knoxville trip with a car rental

  • Finding you a cheap flight from Chicago to McGhee Tyson Airport isn't our only party trick. Browse our car rentals in Knoxville and explore the city on your own terms. We find deals from trusted car rental providers and put them all in one place. You can instantly compare offers and then book with no fees.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.