Flights from Mexico City to Santiago Metropolitan Region

Flight deals from Mexico City to Santiago Metropolitan Region

Looking for cheap tickets from Mexico City to Santiago Metropolitan Region, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Santiago.C$303 per passenger.Departing Sun., Dec. 14.One-way flight with Arajet.Outbound indirect flight with Arajet, departs from Felipe Angeles International on Sun., Dec. 14, arriving in Santiago Arturo Merino Benitez.Price includes taxes and charges.From C$303, select.

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Flying from Mexico City to Santiago Metropolitan Region

Arm yourself with these facts on the fly.

Cheapest flight found	C$303
Cheapest month to fly	December
Average flight time	8 hrs, 1 min
Cheapest airport to fly from	Felipe Angeles International
Most popular airline	LATAM Airlines

How to find cheap flights from Mexico City to Santiago Metropolitan Region

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Mexico City to Santiago Metropolitan Region. Other savvy travellers recently found return flights from C$582 and one-way tickets from C$303 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Felipe Angeles International into Santiago Arturo Merino Benitez

At the moment, the lowest priced flight tickets to Santiago Metropolitan Region are from Felipe Angeles International Airport to Santiago Arturo Merino Benitez Airport.

Fly in December

We crunched the flight calendar and found the cheapest time to fly from Mexico City to Santiago Metropolitan Region is currently December.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Mexico City to anywhere you choose in Santiago Metropolitan Region.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Mexico City to Santiago Metropolitan Region go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Santiago Metropolitan Region to Santiago Metropolitan Region flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Mexico City to Santiago Metropolitan Region flight price?

We looked at all of the upcoming return flights from Mexico City to Santiago Metropolitan Region we could find over the next 12 months. It looks like C$582 is the best price. This is good, compared to the average Santiago Metropolitan Region ticket price of C$581.

What is the cheapest month to fly from Mexico City to Santiago Metropolitan Region?

The cheapest month to fly from Mexico City to Santiago Metropolitan Region is currently December.

Which upcoming date is cheapest to fly from Mexico City to Santiago Metropolitan Region on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Mexico City to Santiago Metropolitan Region on Thursday, December 11, 2025.

Are there any direct flights from Mexico City to Santiago Metropolitan Region?

Mexico City Juarez International Airport offers direct flights to Santiago Metropolitan Region.

If I'm flying from Mexico City, where in Santiago Metropolitan Region is cheapest to fly into?

If you're flying from Mexico City, the cheapest city in Santiago Metropolitan Region to fly into is Santiago. The cheapest airport serving Santiago at the moment is Santiago Arturo Merino Benitez.