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C$53 Cheap Flights from Destin (DSIA) to Knoxville (TYS)

Compare Destin to Knoxville flight deals

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Flight deals from Destin to Knoxville

Looking for a cheap last-minute deal or the best return flight from Destin to Knoxville Airport? If you want to travel next month, return fares start from C$122. Find the lowest prices on one-way and return tickets right here.
Knoxville.C$53 per passenger.Departing Thu., Jul. 9.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu., Jul. 9, arriving in Knoxville.Price includes taxes and charges.From C$53, select.
Knoxville.C$61 per passenger.Departing Mon., Oct. 5.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Mon., Oct. 5, arriving in Knoxville.Price includes taxes and charges.From C$61, select.
Knoxville.C$61 per passenger.Departing Sun., Jun. 28.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Sun., Jun. 28, arriving in Knoxville.Price includes taxes and charges.From C$61, select.
Knoxville.C$61 per passenger.Departing Thu., Sep. 24.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu., Sep. 24, arriving in Knoxville.Price includes taxes and charges.From C$61, select.
Knoxville.C$79 per passenger.Departing Thu., Aug. 20.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu., Aug. 20, arriving in Knoxville.Price includes taxes and charges.From C$79, select.
Knoxville.C$86 per passenger.Departing Thu., Nov. 12.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu., Nov. 12, arriving in Knoxville.Price includes taxes and charges.From C$86, select.
Knoxville.C$93 per passenger.Departing Thu., May 28.One-way flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Destin-Ft Walton Beach on Thu., May 28, arriving in Knoxville.Price includes taxes and charges.From C$93, select.

Find the cheapest month to fly from Destin to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Destin to Knoxville flights are currently cheapest in July.
May
from C$93
Jun.
from C$61
Jul.
from C$53
Aug.
from C$79
Sep.
from C$61
Oct.
from C$61
Nov.
from C$86
Dec.
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Jan.
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Feb.
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Mar.
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Apr.
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Which airlines fly from Destin to Knoxville?

Destin to Knoxville: Alternative routes

Compare routes from Destin to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville
ClosestCheapest
from C$53
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Destin to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundC$53
Cheapest month to flyJuly
Average flight time1 hr, 22 mins
Most popular airlineAllegiant Air
Average flights per week3

Finding cheap flights from Destin to Knoxville: Frequently asked questions

The best price we found for a return flight from Destin to Knoxville is C$108. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 22 minutes is the average flight time from Destin to Knoxville.
Allegiant Air flies direct from Destin to Knoxville.
As of May 2026, there are 3 flights per week flying from Destin to Knoxville.
The cheapest month to fly from Destin to Knoxville is usually July.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Destin to Knoxville Airport on Thursday, July 9, 2026.
Yes – the average flight time is 1 hour and 22 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Knoxville is Allegiant Air .

How to find cheap flights to Knoxville from Destin

Looking for cheap tickets from Destin to Knoxville? Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

  • Simply hit "search." From Delta Air Lines to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Destin to Knoxville. And with us, there are no hidden fees – what you see is what you pay.
  • Compare flight deals to Knoxville from Destin from over 1,000 providers. Then choose the cheapest plane tickets or fastest journeys.
  • Flex your dates to find the best Destin–Knoxville ticket prices. If you're flexible when it comes to your travel dates, use Skyscanner's "Whole month" tool to find the cheapest month, and even day to fly to Knoxville from Destin.
  • Set up a Price Alert. You can easily track the fare of your cheap Destin–Knoxville flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
  • Fly without stops. Only interested in direct flights between Destin and Knoxville? Make sure to tick "Direct flights only" when performing a search. If there are direct flights available on the route, these will appear in the results.
  • Find the cheapest Business Class flights from Destin and Knoxville. We scour the Internet for the best Business, Premium Economy and First Class flight fares to Knoxville, too. Check the difference in price as you search – you might just stumble on a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
  • Include nearby airports in your search. Widen your search for Destin to Knoxville flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save the next time you travel.

    • Combine your flight to Knoxville from Destin with hotels and car rental

    Once you've secured your cheap flight ticket from Destin to Knoxville, discover the best prices and exclusive rates for hotels in Knoxville or nearby. You can also compare hundreds of car rental companies at once so you get the best car rental price for your trip.


Plan the rest of your trip from Destin to Knoxville

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.