C$215 Cheap Flights from Charleston (CHS) to Des Moines (DSM)

Compare Charleston to Des Moines flight deals

Find the cheapest month or even day of the year to fly to Des Moines

Book the best Des Moines fare with no extra fees

Flight deals from Charleston Airport to Des Moines Airport

Looking for a cheap last-minute deal or the best return flight from Charleston to Des Moines? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Charleston to Des Moines

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Charleston to Des Moines flights are currently cheapest in April.

Charleston to Des Moines: Alternative routes

Compare routes from Charleston to Des Moines below. You may find an airport to fly into that's cheaper, faster, or easier than Des Moines.

Charleston to Des Moines: Flight information

The things to know before you go.
Cheapest flight foundC$215
Cheapest month to flyApril

Finding cheap flights from Charleston to Des Moines: Frequently asked questions

The best price we found for a return flight from Charleston to Des Moines is C$563. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Charleston to Des Moines. But we found flights with one or more stops from C$563.
As of March 2026, there are no flights flying from Charleston to Des Moines.
The cheapest month to fly from Charleston to Des Moines is usually May.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Charleston Airport to Des Moines Airport on Thursday, May 21, 2026.
No airlines currently offer direct flights between Charleston Airport and Des Moines Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Des Moines but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Des Moines is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Southwest Airlines offers the cheapest flight tickets to Des Moines.

Traveling from Charleston International Airport (CHS) to Des Moines International Airport (DSM): what you need to know

  • Heading off during a peak period like school or public holidays? Expect longer lines at check-in and security. For peace of mind, arrive up to four hours before international flights and two hours ahead of domestic departures.

  • If you want to break up your flight from Charleston International Airport to Des Moines International Airport, add a stopover to your trip. Simply uncheck 'Direct flights only' to find a destination that interests you. Popular stopovers on the CHS - DSM route include:

    • Charlotte Douglas International Airport

    • Detroit Metropolitan Wayne County Airport

    • O'Hare International Airport

How to find the cheapest flights from Charleston International Airport (CHS) to Des Moines International Airport (DSM)

  • C$215 is currently the lowest price for a one-way ticket from Charleston International Airport to Des Moines International Airport. A return flight starts at C$563. These fares may change based on availability.

  • It's usually best to book early if you want to find cheap flight tickets from CHS to DSM. That's because flight prices are based on demand, which tends to rise closer to departure.

  • Getting cheap flight tickets from Charleston International Airport to Des Moines International Airport is easier if you're flexible with your trip dates. Try using the 'Whole month' function to see the lowest fares across every month and snap up a great deal.

  • Getting a cheap ticket from CHS to DSM is a piece of cake with Price Alerts. Simply create one of these automatic alerts and we'll notify you as soon as the price has dropped.

  • Use filters to tailor your flights from Charleston International Airport to Des Moines International Airport. Simply select your preferred departure and arrival times, number of stops and airlines. Or sort your results by 'Cheapest' to see the best deals.

Handy information about Charleston International Airport (CHS)

  • Traveling from central Charleston to Charleston International Airport takes approximately 3 hours and 36 minutes by public transport. If you ride-share, drive or grab a cab, you'll cover the 21 kilometres in 28 minutes or so, depending on traffic conditions.

  • Booked an early flight from Charleston International Airport to Des Moines International Airport? Avoid the hassle of rushing to the terminal (and sneak in some extra snooze time) by picking one of these stays close to CHS:

Arriving at Des Moines International Airport (DSM)

Getting from Des Moines International Airport (DSM) to central Des Moines

  • From Des Moines International Airport, Des Moines is approximately 10 kilometres away. It takes around 14 minutes to get to the center driving.

  • If you're using public transport, expect a journey time of about 43 minutes.

When to fly to Des Moines International Airport (DSM)

  • It's time to plan your dates for your flight from Charleston International Airport to Des Moines International Airport. July is the busiest month to visit Des Moines. If you want a more low-key vibe, go in April.

  • The warmest month in Des Moines is July, with the temperature ranging between 15ºC and 31ºC. Lock in your flights from Charleston International Airport to Des Moines International Airport in this month if this is the type of weather you enjoy.

  • If you want to travel in cooler conditions, look for a cheap ticket from CHS to DSM in January. Average temperatures are between -13ºC and 2ºC then.

More about Des Moines

Complete your Des Moines trip with hotels and a car rental

  • After you've secured your cheap ticket to Des Moines International Airport, browse our low prices and exclusive offers on hotels. You can also compare a range of car rental companies in one place to get the best car rental price for your Des Moines vacation.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.