C$342 Cheap Flights from Guayaquil (GYE) to Santo Domingo (SDQA)

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Flight deals from Guayaquil to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Guayaquil Airport to Santo Domingo? If you want to travel next month, return fares start from C$635. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Guayaquil to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Guayaquil to Santo Domingo flights are currently cheapest in May.

Alternative Guayaquil to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Guayaquil to Santo Domingo? You could fly into the following airports instead.

Guayaquil to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight foundC$342
Cheapest month to flyMay

Finding cheap flights from Guayaquil to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Guayaquil to Santo Domingo is C$631. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Guayaquil to Santo Domingo. But we found flights with one or more stops from C$631.
As of May 2026, there are no flights flying from Guayaquil to Santo Domingo.
The cheapest month to fly from Guayaquil to Santo Domingo is usually October.
If you're flying from Guayaquil Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from C$631.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Guayaquil Airport to Santo Domingo on Friday, October 9, 2026.
No airlines currently offer direct flights between Guayaquil Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 27°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Avianca offers the cheapest flight tickets to Santo Domingo.

Flying from Jose Joaquin de Olmedo Airport (GYE) to Santo Domingo: what you need to know

  • Expect to be travelling for 3 hours 48 minutes. That's the average time for a direct flight from Jose Joaquin de Olmedo Airport to Santo Domingo.

  • Jose Joaquin de Olmedo Airport is located in Guayaquil. Based in the UTC-4 timezone, Santo Domingo is 1 hour ahead of Guayaquil.

  • Jose Joaquin de Olmedo Airport (GYE) to Las Americas International Airport (SDQ) is the most traveled route, with 3 weekly departures to choose from. If you prefer a later start to the day, the last flight from GYE to SDQ is with Arajet at 23:04. Go for the first departure operated by Arajet at 05:45 if you want to get on your way earlier.

  • Leave plenty of time to catch your flight from GYE to Santo Domingo. A good rule of thumb is to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • During popular months such as August, you'll want to get to the airport even earlier. Plan to arrive two hours before a domestic departure and four hours ahead for an international flight whenever you're flying during high season in general.

  • Nonstop flights from Jose Joaquin de Olmedo Airport (GYE) to Santo Domingo are available for booking. Las Americas International Airport (SDQ) is where you'll arrive.

  • Be on the lookout for offers from Arajet. This airline has direct flights from Jose Joaquin de Olmedo Airport to Santo Domingo.

  • Consider adding a stopover to potentially find a cheaper flight from GYE to Santo Domingo. Just deselect 'Direct flights only' when browsing the departures. Break up the journey at one of these airports:

    • El Dorado International Airport (BOG)

    • Tocumen International Airport (PTY)

    • Miami International Airport (MIA)

  • To visit Dominican Republic for tourism purposes, you'll need an embassy visa if you hold a passport from Ecuador. However, visa rules are subject to change and other documentation may be needed depending on the length and purpose of your visit. Always check the most up-to-date guidelines before booking your cheap ticket from Jose Joaquin de Olmedo Airport to Santo Domingo.

  • Located around 6 kilometres from central Guayaquil, GYE can be reached in about 10 minutes by car (depending on traffic). The same journey by public transport takes roughly 20 minutes.

  • Want a stress-free start to your journey? Stay near GYE. Whether you're catching an early flight from Jose Joaquin de Olmedo Airport to Santo Domingo or just don't want to be rushed, these hotels are ideal:

How to find the cheapest flights from Jose Joaquin de Olmedo Airport (GYE) to Santo Domingo

  • C$342 is the cheapest price we've found for a one-way ticket from Jose Joaquin de Olmedo Airport to Santo Domingo. For a return flight on this route, the best price is C$631. Depending on the availability when you book, these fares can change.

  • To secure cheap tickets from GYE to Santo Domingo, reserve your journey 4 months ahead of your departure.

  • The cheapest month for tickets from Jose Joaquin de Olmedo Airport to Santo Domingo is December. You can easily compare prices using the 'Whole month' tool to find the cheapest day to fly.

  • Sign into your online account or use the app to set up a Price Alert. You'll be notified straight away if there's a cheaper deal on this route. It doesn't take long, and it'll save you from looking for cheap tickets from GYE to Santo Domingo every day.

  • Tailor your travel plans with filters. Pick your arrival and departure times, total journey duration and airlines. You can also sort results by 'Cheapest,' 'Best' or 'Fastest' flights from Jose Joaquin de Olmedo Airport to Santo Domingo.

Airports in Santo Domingo

Las Americas International Airport (SDQ)

  • Las Americas International Airport (SDQ) is around 32 kilometres from central Santo Domingo. With your own car rental or in a cab, the drive is about 31 minutes.

  • Consider booking a hotel close to SDQ if you're taking a late flight from Jose Joaquin de Olmedo Airport to Santo Domingo. Choose one of these accommodation options and avoid the hassle of a long transfer:

Dr. Joaquin Balaguer International Airport (JBQ)

  • Once your flight from Jose Joaquin de Olmedo Airport to Santo Domingo has hit the tarmac, you can make your way to the city centre in around 27 minutes by car. Central Santo Domingo is approximately 19 kilometres from Dr. Joaquin Balaguer International Airport (JBQ).

  • Settle in and unpack not long after your flight from GYE to Santo Domingo at Confortable, Quiet And Secure. This comfortable accommodation option is a quick drive from JBQ.

Best time to go to Santo Domingo

  • August is the busiest month for flights from Jose Joaquin de Olmedo Airport to Santo Domingo. To escape the crowds, head to Santo Domingo in May when things are quieter.

  • Lock in your flight from Jose Joaquin de Olmedo Airport to Santo Domingo for September to experience the city during its warmest month. You can expect temperatures to range from 23ºC to 33ºC.

  • If you like travelling in cooler conditions, lock in a cheap flight from GYE to Santo Domingo in February when temperatures average between 19ºC and 29ºC.

More about Santo Domingo

  • When it comes to searching for somewhere to rest your head, you'll find the most popular stays in Santo Domingo right here. Browse these hotels as soon as you've locked in your flight from Jose Joaquin de Olmedo Airport to Santo Domingo:

  • Every great vacation has to include some sightseeing. Alcazar de Colon, National Pantheon (Pantheon Nacional) and National Palace are must-do's during your Santo Domingo adventure.

Complete your Santo Domingo trip with a car rental

  • We use the same magic that helped you find your cheap flight from Jose Joaquin de Olmedo Airport to Santo Domingo to track down awesome deals on car rentals. Search for your ride in seconds and compare offers in one place. Plus you'll find everything you need to know about car rentals in Santo Domingo, from the most popular rental company to the average daily price.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.