Flights from Key West to South Carolina

Flight deals from Key West to South Carolina

Looking for cheap tickets from Key West to South Carolina, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Greenville.C$277 per passenger.Departing Wed., Mar. 18.One-way flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departs from Key West International on Wed., Mar. 18, arriving in Greenville-Spartanburg.Price includes taxes and charges.From C$277, select.

Charleston.C$391 per passenger.Departing Mon., Dec. 7.One-way flight with Delta.Outbound indirect flight with Delta, departs from Key West International on Mon., Dec. 7, arriving in Charleston.Price includes taxes and charges.From C$391, select.

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Flying from Key West to South Carolina

Arm yourself with these facts on the fly.

Cheapest flight found	C$277
Cheapest month to fly	March
Cheapest airport to fly from	Key West International

How to find cheap flights from Key West to South Carolina

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Key West to South Carolina. Other savvy travellers recently found return flights from C$318 and one-way tickets from C$277 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Key West International into Charleston

At the moment, the lowest priced flight tickets to South Carolina are from Key West International Airport to Charleston Airport.

Fly in February

We crunched the flight calendar and found the cheapest time to fly from Key West to South Carolina is currently February.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Key West to anywhere you choose in South Carolina.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Key West to South Carolina go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the South Carolina to South Carolina flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Key West to South Carolina flight price?

We looked at all of the upcoming return flights from Key West to South Carolina we could find over the next 12 months. It looks like C$318 is the best price. This is good, compared to the average South Carolina ticket price of C$364.

What is the cheapest month to fly from Key West to South Carolina?

The cheapest month to fly from Key West to Myrtle Beach International Airport is currently February. The cheapest month to fly from Key West to Charleston Airport is usually February. And the cheapest month to fly from Key West to Columbia Metropolitan Airport is usually February.

Which upcoming date is cheapest to fly from Key West to South Carolina on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Key West to South Carolina on Wednesday, February 18, 2026.

Are there any direct flights from Key West to South Carolina?

Currently, there aren't any direct flights from Key West to South Carolina, but you can still fly with a stopover.

If I'm flying from Key West, where in South Carolina is cheapest to fly into?

If you're flying from Key West, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.