Flights from Panama City to Santiago Metropolitan Region

Travelers and cabin class

Flight deals from Panama City to Santiago Metropolitan Region

Looking for cheap flights from Panama City to Santiago Metropolitan Region, or a last-minute trip? Find the lowest prices on one-way and round-trip flights right here.

Flying from Panama City to Santiago Metropolitan Region

Arm yourself with these facts on the fly.
Cheapest flight foundC$389, Santiago
Cheapest month to flyJuly
Average flight time6 hrs, 34 mins
Cheapest airport to fly fromPanama City Tocumen International
Most popular airlineCopa

Frequently asked questions

We looked at all of the upcoming round-trip flights from Panama City to Santiago Metropolitan Region we could find over the next 12 months. It looks like C$708 is the best price. This is good, compared to the average Santiago Metropolitan Region ticket price of C$857.
The cheapest month to fly from Panama City to Santiago Metropolitan Region is currently June.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Santiago Metropolitan Region on Wednesday, June 18, 2025.
Panama City Tocumen International Airport offers direct flights to Santiago Metropolitan Region.
If you're flying from Panama City, the cheapest city in Santiago Metropolitan Region to fly into is Santiago. The cheapest airport serving Santiago at the moment is Santiago Arturo Merino Benitez.
The average flight time between Panama City and Santiago Metropolitan Region is 6 hours and 34 minutes.