C$138 Cheap Flights from Santo Domingo (SDQA) to Medellin (MDEA)

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Flight deals from Santo Domingo to Medellin

Looking for a cheap last-minute deal or the best return flight from Santo Domingo to Medellin? If you want to travel next month, return fares start from C$327. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Santo Domingo to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santo Domingo to Medellin flights are currently cheapest in June.

Which airlines fly from Santo Domingo to Medellin?

Alternative Santo Domingo to Medellin routes

Looking for the cheapest, fastest or easiest route from Santo Domingo to Medellin? You could fly into the following airports instead.

Santo Domingo to Medellin: Flight information

The things to know before you go.
Cheapest flight foundC$138
Cheapest month to flyJune
Average flight time2 hrs, 32 mins
Most popular airlineArajet
Average flights per week35

Finding cheap flights from Santo Domingo to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
The best price we found for a return flight from Santo Domingo to Medellin is C$298. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 32 minutes is the average flight time from Santo Domingo to Medellin.
Arajet, World Ticket Ltd and Copa Airlines Colombia fly direct from Santo Domingo to Medellin.
As of March 2026, there are 35 flights per week flying from Santo Domingo to Medellin.
The cheapest month to fly from Santo Domingo to Medellin is usually June.
If you're flying from Santo Domingo, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from C$298.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santo Domingo to Medellin on Sunday, June 7, 2026.
Yes – the average flight time is 2 hours and 32 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.
In March, the average temperature is usually around 19°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.
The cheapest airline that flies to Medellin is Arajet .

Flying from Santo Domingo to Medellin: what you need to know

  • There are a couple of main airports to choose from in Santo Domingo. Explore your options departing from Las Americas International Airport (SDQ) or Dr. Joaquin Balaguer International Airport (JBQ) when booking your flight from Santo Domingo to Medellin.

  • Jose Maria Cordova International Airport (MDE) is the major hub where you can touch down in Medellin.

  • A direct flight from Santo Domingo to Medellin takes an average of 2 hours 27 minutes. The timezone in Medellin is UTC-5, making it 1 hour behind Santo Domingo.

  • The most popular route for flights from Santo Domingo to Medellin is from Las Americas International Airport (SDQ) to Jose Maria Cordova International Airport (MDE). You can select from 61 services every week between these two airports. If you'd like to get going as soon as possible, the earliest flight from SDQ to MDE is the 11:37 Wingo service. If you have other commitments or plans on your day of travel, the last departure is at 21:28 with Wingo.

  • To ensure you get on your flight from Santo Domingo to Medellin, leave plenty of time for things like baggage drop and finding your gate. Arriving two hours ahead of international departures and an hour before domestic flights is the general rule.

  • During popular months like August, it's best to get to the airport even earlier. Plan to arrive two hours before domestic departures and four hours ahead of international flights when you fly during a peak period in general.

  • You can visit Colombia for tourism purposes without a visa if you hold a passport from Dominican Republic. But before organizing your cheap flight from Santo Domingo to Medellin, make sure you're up to date with the latest guidelines. Visa rules are subject to change, and you may need some documentation if your trip is for work or other reasons.

Flying from Santo Domingo

Las Americas International Airport (SDQ)

  • Set out from Las Americas International Airport (SDQ) on a nonstop flight from Santo Domingo to Medellin. From SDQ, you can land directly at Jose Maria Cordova International Airport (MDE).

  • Book your direct flight from Santo Domingo to Medellin with Wingo. This popular airline operates services from SDQ.

  • A stopover is the ideal opportunity to take a travel break — and maybe even visit a new city. When searching for flights from Santo Domingo to Medellin leaving from Las Americas International Airport, uncheck the 'Direct flights only' box to see where you can stop along the way. Popular options include:

    • El Dorado International Airport (BOG)

    • Simon Bolivar International Airport (CCS)

    • Rafael Nunez International Airport (CTG)

  • To reach SDQ from central Santo Domingo, it'll take about 31 minutes if you're planning to drive. Of course, this depends on traffic. It's approximately 32 kilometres from the airport to the city centre.

  • Want an easy start to your trip? Stay near Las Americas International Airport. Whether you have an early flight from Santo Domingo to Medellin or want to avoid feeling rushed, these hotels have you covered:

Dr. Joaquin Balaguer International Airport (JBQ)

  • Make the most of your vacation with a stopover on your flight from Santo Domingo to Medellin. Visit friends or family or cross another city off your list. Whatever you decide to do, here's where you can stop between Las Americas International Airport and Medellin:

    • El Dorado International Airport (BOG)

    • Simon Bolivar International Airport (CCS)

    • Rafael Nunez International Airport (CTG)

  • Driving from central Santo Domingo to JBQ usually takes 27 minutes, depending on traffic. It's roughly 19 kilometres from the city centre to the airport.

  • It's your vacation, so why not spend another night away at a hotel near Dr. Joaquin Balaguer International Airport? Before your flight from Santo Domingo to Medellin, think about staying at Confortable, Quiet And Secure.

Arriving in Medellin

Jose Maria Cordova International Airport (MDE)

Enrique Olaya Herrera Airport (EOH)

  • Central Medellin is approximately 6 kilometres from Enrique Olaya Herrera Airport (EOH). After your flight from Santo Domingo to Medellin has touched down and you've made your way to arrivals, expect a drive of about 16 minutes.

  • If you're travelling on public transport, it'll take approximately 31 minutes.

  • After your flight from Santo Domingo to Medellin, tuck yourself in at a hotel near EOH. These are some comfortable accommodation options that'll help you switch to relaxation mode:

How to find the cheapest flights from Santo Domingo to Medellin

  • C$138 is currently the best price for a one-way ticket from Santo Domingo to Medellin. Return flights start at C$298. These prices may change depending on availability and demand.

  • Get cheap flights from Santo Domingo to Medellin by booking 9 months ahead. Based on our research, that's the sweet spot for finding the biggest deals.

  • Organize your trip for May. That's the cheapest month for tickets from Santo Domingo to Medellin. If your travel dates are flexible, use the 'Whole month' tool to find the lowest price across each month.

  • Getting a cheap ticket from Santo Domingo to Medellin couldn't be easier with Price Alerts. Simply create one of these automatic alerts and we'll notify you when the price has dropped.

  • Use filters to tailor your flights from Santo Domingo to Medellin. Pick your ideal departure and arrival times, airlines and number of stops. Alternatively, sort your results by 'Cheapest' to find the best deals.

Best time to go to Medellin

  • April is the quietest month for flights from Santo Domingo to Medellin, while August is the most popular. Pick the ideal time to go to Medellin based on whether you like a bustling atmosphere or a more laid-back vibe.

  • Schedule your flight from Santo Domingo to Medellin for August if you want to explore the city during its warmest month. You can expect temperatures in Medellin to range from 11ºC to 27ºC.

  • Search for cheap flights from Santo Domingo to Medellin in July if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 11ºC and 27ºC on average.

More about Medellin

  • When it comes to looking for somewhere to lay your head, you'll find the top stays in Medellin right here. Check out these hotels after locking in your flight from Santo Domingo to Medellin:

  • Parque Arvi and Comuna 13 are a couple of leading attractions to put on your Medellin itinerary. Keep the momentum going by heading to Botero Plaza.

Complete your Medellin trip with a car rental

  • We use the same magic that helped you find your cheap flight from Santo Domingo to Medellin to track down incredible deals on car rentals. Search for your ride in seconds and easily compare your options. Plus we give you all the info you need to drive in Medellin, from the most popular car rental to the average daily price.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.