C$197 Cheap Flights from Buffalo Niagara (BUF) to Des Moines (DSM)

Compare Buffalo Niagara to Des Moines flight deals

Find the cheapest month or even day of the year to fly to Des Moines

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Find the cheapest month to fly from Buffalo Niagara to Des Moines

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Buffalo Niagara to Des Moines flights are currently cheapest in May.

Buffalo Niagara to Des Moines: Alternative routes

Compare routes from Buffalo Niagara to Des Moines below. You may find an airport to fly into that's cheaper, faster, or easier than Des Moines.

Buffalo to Des Moines: Flight information

The things to know before you go.
Cheapest flight foundC$197
Cheapest month to flyMay

Finding cheap flights from Buffalo Niagara to Des Moines: Frequently asked questions

The best price we found for a return flight from Buffalo Niagara to Des Moines is C$558. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Buffalo Niagara to Des Moines. But we found flights with one or more stops from C$558.
As of April 2026, there are no flights flying from Buffalo Niagara to Des Moines.
The cheapest month to fly from Buffalo Niagara to Des Moines is usually April.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Buffalo Niagara Airport to Des Moines Airport on Thursday, April 30, 2026.
No airlines currently offer direct flights between Buffalo Niagara Airport and Des Moines Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Des Moines but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Des Moines is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Des Moines.

Traveling from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM): what you need to know

  • Delays at security and check-in are likely if you're heading away during high season, so allow some extra breathing room. A good rule of thumb for peak times? Arrive up to four hours early for international flights and at least two hours for domestic departures.

  • To break up your flight from Buffalo Niagara International Airport to Des Moines International Airport, think about adding a stopover. Simply deselect 'Direct flights only' and find a city that appeals to you. The most popular stopovers on the BUF - DSM route include:

    • Nashville International Airport

    • Detroit Metropolitan Wayne County Airport

    • O'Hare International Airport

How to find the cheapest flights from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM)

  • The lowest price we've seen for a one-way ticket from Buffalo Niagara International Airport to Des Moines International Airport is C$197. For a return flight on this route, the best price is C$558. Depending on the availability and when you book, these fares may change.

  • Don't wait until the last moment. You're more likely to find cheap flight tickets from BUF to DSM if you book in advance. Airlines often have some amazing early bird deals.

  • The 'Whole month' tool shows you the cheapest flight tickets from Buffalo Niagara International Airport to Des Moines International Airport throughout the month. It's a good way to snap up a bargain if your trip dates are flexible.

  • Sign into your online account or use the app to set up a Price Alert. We'll notify you right away if there's a cheaper deal on this route. It's simple to do, and it'll save you the hassle of searching for cheap flight tickets from BUF to DSM every day.

  • Use filters to tailor your flights from Buffalo Niagara International Airport to Des Moines International Airport. Select your preferred arrival and departure times, number of stops and airlines. Alternatively, sort your results by 'Cheapest' to see the best deals.

Handy information about Buffalo Niagara International Airport (BUF)

  • Buffalo Niagara International Airport is around 18 kilometres from central Buffalo. If you're catching a cab, ride-sharing or driving from the center, it'll take 21 minutes or so to get there, depending on traffic conditions. If you're taking public transport, expect the journey time to be around 1 hour and 15 minutes.

  • Catching an early flight from Buffalo Niagara International Airport to Des Moines International Airport? Avoid rushing to the airport (and sneak in some extra precious sleep) by choosing one of these hotels close to BUF:

Arriving at Des Moines International Airport (DSM)

Getting from Des Moines International Airport (DSM) to central Des Moines

  • Des Moines International Airport to the center of Des Moines is around 14 minutes in a car. It's approximately 10 kilometres away. Discover what options are available, such as cabs, car rentals or ride-sharing services.

  • It takes roughly 43 minutes if you're using public transport.

When to fly to Des Moines International Airport (DSM)

  • It's time to choose your travel dates for your flight from Buffalo Niagara International Airport to Des Moines International Airport. July is the busiest month to visit Des Moines. If you prefer a quieter vibe, go in April.

  • Before locking in your flight from Buffalo Niagara International Airport to Des Moines International Airport, consider the type of weather you enjoy. July is the warmest month in Des Moines, with the temperature ranging from 15ºC to 31ºC.

  • If you like traveling in cooler conditions, search for a cheap ticket from BUF to DSM in January. Average temperatures are between -13ºC and 2ºC then.

More about Des Moines

Complete your Des Moines trip with hotels and a car rental

  • You've booked a cheap ticket to Des Moines International Airport — next up is finding a great stay, and maybe even your own set of wheels. We've compared prices across hundreds of companies to bring you the top hotels and car rental deals in Des Moines.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.