Cheap flights from Santiago to Panama City Tocumen International

How to find cheap flights to Panama City (PTY) from Santiago (STI) in 2025

Looking for cheap tickets from Santiago to Panama City Tocumen International? Round-trip tickets start from C$1,010 and one-way flights to Panama City Tocumen International from Santiago start from C$350

Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

• Simply hit "search." From American Airlines to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Santiago to Panama City Tocumen. And with us, there are no hidden fees – what you see is what you pay.
• Compare flight deals to Panama City from Santiago from over 1,000 providers. Then choose the cheapest or fastest plane tickets. Flight tickets to Panama City start from C$350 one-way.
• Flex your dates to find the best STI–PTY ticket prices. If you are flexible when it comes to your travel dates, use Skyscanner's "Whole month" tool to find the cheapest month, and even day to fly to Panama City Tocumen International from Santiago.
• Set up a Price Alert. You can easily track the fare of your cheap Santiago-Panama City Tocumen flights by creating an alert. Whenever prices go up or down, you'll get an email or push notification to help make sure you get the best possible flight deal.
• Fly without stops. Only interested in direct flights between Santiago and Panama City Tocumen International? Make sure to check "Direct flights only" when performing a search. If there are direct flights available on the route, these will appear in the results. Airlines that fly direct include: Copa
• Find the cheapest Business class flights from Santiago and Panama City Tocumen International. We scour the Internet for the best Business, Premium Economy and First Class flight fares to Panama City, too. Check the difference in price as you search – you might just chance upon a last-minute deal. Note that not all cabin classes are available for every destination or airline.
• Flexible on when you travel? The cheapest month to fly from Santiago to Panama City Tocumen International is September.
• Include nearby airports in your search. Widen your search for Santiago to Panama City Tocumen International flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save next time you travel.
• Search for cheap flights regardless of where you are. To get the best flight booking experience when out and about, download the app and search for plane tickets between Santiago and Panama City Tocumen International whenever you want.

Combine your flight to Panama City Tocumen International from Santiago with hotels and car rental

Once you've secured your cheap flight ticket from Santiago to Panama City Tocumen International, discover the best prices and exclusive rates for hotels in Panama City or nearby. You can also compare hundreds of car rental companies all at once so you get the best car rental price for your trip.