C$336 Cheap Flights from Sao Paulo (SAOA) to Panama City (PTYA)

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Flight deals from Sao Paulo to Panama City

Looking for a cheap last-minute deal or the best return flight from Sao Paulo to Panama City? If you want to travel next month, return fares start from C$652. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Sao Paulo to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Sao Paulo to Panama City flights are currently cheapest in May.

Which airlines fly from Sao Paulo to Panama City?

Alternative Sao Paulo to Panama City routes

Looking for the cheapest, fastest or easiest route from Sao Paulo to Panama City? You could fly into the following airports instead.

Sao Paulo to Panama City: Flight information

The things to know before you go.
Cheapest flight foundC$336
Cheapest month to flyMay
Average flight time6 hrs, 51 mins
Most popular airlineCopa
Average flights per week155

Finding cheap flights from Sao Paulo to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Sao Paulo to Panama City is C$645. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 51 minutes is the average flight time from Sao Paulo to Panama City.
Copa, GOL Linhas Aéreas and Azul Airlines fly direct from Sao Paulo to Panama City.
As of April 2026, there are 155 flights per week flying from Sao Paulo to Panama City.
The cheapest month to fly from Sao Paulo to Panama City is usually June.
If you're flying from Sao Paulo, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from C$645.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Sao Paulo to Panama City on Sunday, June 7, 2026.
Yes – the average flight time is 6 hours and 51 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
The cheapest airline that flies to Panama City is Avianca. And the cheapest airline that flies to Balboa Airport is Copa.

Travelling from Sao Paulo to Panama City: what you need to know

  • Start your travel planning by considering where you'll take off for your flight from Sao Paulo to Panama City. Sao Paulo-Guarulhos International Airport (GRU) and Viracopos Airport (VCP) are the main airports in Sao Paulo.

  • Tocumen International Airport (PTY) and Panama Pacifico Airport (BLB) are Panama City's major gateways.

  • The average length of a direct flight from Sao Paulo to Panama City is 7 hours 3 minutes. Panama City's timezone is UTC-5, which makes Panama City 2 hours behind Sao Paulo.

  • With 44 flights a week between the two airports, Sao Paulo-Guarulhos International Airport (GRU) to Tocumen International Airport (PTY) is the busiest route. Hop on the earliest flight from Sao Paulo to Panama City with Copa Airlines at 01:25. If you're keen to make the most of your day before you fly, the latest departure from GRU to PTY is with Copa Airlines at 11:35.

  • Leave plenty of time to catch your flight from Sao Paulo to Panama City. As a general rule, turn up two hours before international departures and an hour ahead for domestic flights.

  • During popular months like July, it's a good idea to get to the airport well in advance. Plan to arrive two hours before a domestic departure and four hours ahead of an international flight when you travel during peak periods in general.

  • You don't need a visa for Panama if you hold a passport from Brazil and are travelling for tourism purposes. Visa and travel documentation requirements are subject to change. So before reserving your cheap flights from Sao Paulo to Panama City, be sure to check with your airline and your destination country's local consulate or embassy for the latest rules.

Flying from Sao Paulo

Sao Paulo-Guarulhos International Airport (GRU)

  • Set out from Sao Paulo-Guarulhos International Airport (GRU) on a nonstop flight from Sao Paulo to Panama City. From GRU, you can land directly at Tocumen International Airport (PTY).

  • Copa Airlines is a leading airline that offers direct flights from Sao Paulo to Panama City jetting out of GRU.

  • We make it a breeze to book a flight from Sao Paulo to Panama City that includes a stopover. To see all your options leaving from Sao Paulo-Guarulhos International Airport, uncheck 'Direct flights only.' Then, simply pick a flight offering a stop long enough to explore the city of your choice. Some popular stopovers include:

    • Ministro Pistarini Airport (EZE)

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

  • GRU is about 26 kilometres from central Sao Paulo. If you're catching a cab, driving or ride-sharing from the centre, it'll take you 32 minutes or so to get there, depending on traffic. If you're planning to take public transport, expect the travel time to be approximately 1 hour and 22 minutes.

  • Searching for a convenient hotel close to Sao Paulo-Guarulhos International Airport? If you're catching an early flight from Sao Paulo to Panama City, these accommodation options will have you sleeping moments from check-in:

Viracopos Airport (VCP)

  • Visit family or friends or just take a moment to stretch your legs with a stopover. If you'd like to split up your flight from Sao Paulo to Panama City, check out these options when departing from Sao Paulo-Guarulhos International Airport:

    • Ministro Pistarini Airport (EZE)

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

  • On public transport, you can travel from central Sao Paulo to VCP in about 3 hours and 25 minutes. The terminal is roughly 97 kilometres away, and making the journey by car takes approximately 1 hour and 16 minutes.

  • You're off on vacation, so why not extend it with an extra night away from home? Consider kicking back in one of these hotels near Viracopos Airport the day before your flight from Sao Paulo to Panama City:

Arriving in Panama City

Tocumen International Airport (PTY)

Marcos A. Gelabert International Airport (PAC)

How to find the cheapest flights from Sao Paulo to Panama City

  • The cheapest price we've seen for a one-way ticket from Sao Paulo to Panama City is C$336. For a return flight on this route, the best price is C$645. Depending on when and how early you book, these fares could change.

  • Lock in cheap flights from Sao Paulo to Panama City by booking 1 month ahead. Based on our research, that's the sweet spot for picking up a bargain.

  • The cheapest month for tickets from Sao Paulo to Panama City is September. Compare prices using the 'Whole month' tool to find the cheapest travel date.

  • Create a Price Alert for cheap flights from Sao Paulo to Panama City. You don't need to check every day to see if prices have fallen. We'll notify you the moment the price changes.

  • Use filters to tailor your flights from Sao Paulo to Panama City. Pick your preferred departure and arrival times, number of stops and airlines. Alternatively, sort your results by 'Cheapest' to find the best deals.

Best time to go to Panama City

  • June is the busiest month for flights from Sao Paulo to Panama City. To escape the crowds, go to Panama City in February.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC and 32ºC. Lock in your flights from Sao Paulo to Panama City in this month if you like this kind of weather.

  • February sees average temperatures of between 22ºC and 31ºC. Look for cheap flights from Sao Paulo to Panama City sometime then if you like travelling in cooler conditions.

More about Panama City

  • Start your Panama City trip off on the right foot by choosing the ideal place to stay. Once you've booked your flight from Sao Paulo to Panama City, check out our selection of hotels including:

  • Panama Canal Museum and Casco Viejo are just two of the major attractions to add to your Panama City travel itinerary. Continue your sightseeing adventures at Cinta Costera.

Complete your Panama City trip with a car rental

  • Finding you a cheap flight from Sao Paulo to Panama City isn't the only trick up our sleeve. Check out our car rentals in Panama City and explore the city on your own terms. We search for deals from trusted car rental companies and put them all in one place. Instantly compare rates and then book with no fees.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.