C$344 Cheap Flights from Panama City (PTYA) to Raleigh \u002F Durham (RDU)

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Flight deals from Panama City to Raleigh / Durham

Looking for a cheap last-minute deal or the best round-trip flight from Panama City to Raleigh / Durham? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Panama City to Raleigh / Durham

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Raleigh / Durham flights are currently cheapest in March.

Direct flights from Panama City to Raleigh / Durham

Panama City to Raleigh / Durham: Alternative routes

Compare routes from Panama City to Durham below. You may find an airport to fly into that's cheaper, faster, or easier than Raleigh / Durham.

Panama City to Durham: Flight information

The things to know before you go.
Cheapest flight foundC$344
Cheapest month to flyMarch
Average flight time4 hrs, 24 mins
Most popular airlineCopa
Average flights per week18

Finding cheap flights from Panama City to Raleigh / Durham: Frequently asked questions

The best price we found for a return flight from Panama City to Raleigh / Durham is C$577. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
4 hours and 24 minutes is the average flight time from Panama City to Raleigh / Durham.
Copa flies direct from Panama City to Raleigh / Durham.
As of January 2026, there are 9 flights per week flying from Panama City to Raleigh / Durham.
The cheapest month to fly from Panama City to Raleigh / Durham is usually February.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Raleigh / Durham Airport on Monday, February 9, 2026.
Yes – the average flight time is 4 hours and 24 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Raleigh / Durham but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Durham is around 40 days in advance, so don’t leave your flight to the last minute.

Travelling from Panama City to Raleigh-Durham International Airport (RDU): what you need to know

  • Panama City is home to two main airports where you can start your adventure. Check out your options for reserving a flight from Panama City to Raleigh-Durham International Airport (RDU) leaving from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB).

  • The timezone in Durham is UTC-4, which is 1 hour ahead of Panama City. Raleigh-Durham International Airport is located in Durham.

  • For a smooth journey, arrive at the airport two hours ahead of international flights and an hour before domestic departures. This way, you'll have plenty of time to catch your flight from Panama City to RDU.

  • During popular months like June, you'll want to get to the airport earlier. Arrive two hours before domestic departures and four hours ahead for an international flight whenever you're flying during high season in general.

Airports in Panama City

Tocumen International Airport (PTY)

  • We make it a cinch to plan a flight from Panama City to RDU that includes a stopover. To see all the options departing from Tocumen International Airport (PTY), deselect 'Direct flights only.' Then, simply pick a flight that has a stop long enough to see the sights of your chosen city. Major stopovers between PTY and RDU include:

    • Miami International Airport (MIA)

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Tampa International Airport (TPA)

  • The distance from central Panama City to PTY is about 21 kilometres. Check out Google Maps for the best route, whether you plan to drive or take public transport.

  • After a leisurely start to your break? Stay near Tocumen International Airport. Whether you have an early flight from Panama City to Raleigh-Durham International Airport or just don't like being rushed, these hotels are just the thing:

Panama Pacifico Airport (BLB)

  • Prefer to leave from Panama Pacifico Airport (BLB)? You can book a direct flight from Panama City to Raleigh-Durham International Airport (RDU) out of this popular hub.

  • BLB is roughly 16 kilometres from central Panama City. It'll take 22 minutes or so to get to the airport when driving from the city centre.

  • You're off on vacation, so why not spend an extra night away from home? Consider kicking back in one of these hotels near Panama Pacifico Airport the day before your flight from Panama City to RDU:

About Raleigh-Durham International Airport (RDU)

Getting from Raleigh-Durham International Airport (RDU) to central Durham

  • From Raleigh-Durham International Airport, Durham is approximately 23 kilometres away. It takes around 18 minutes to get to the centre driving.

  • Travelling on public transport takes about 1 hour and 10 minutes.

How to find the cheapest flights from Panama City to Raleigh-Durham International Airport (RDU)

  • The lowest price we've found for a one-way ticket from Panama City to Raleigh-Durham International Airport is C$344. The cheapest price for a return flight is C$577. Keep in mind fares can change due to availability at the time of booking.

  • It's often best to book ahead of time if you want to find flight tickets from Panama City to RDU. That's because flight prices are based on demand, which tends to rise closer to the date of departure.

  • The 'Whole month' tool shows you the cheapest tickets from Panama City to Raleigh-Durham International Airport across every month. It's an easy way to find a bargain if your travel plans are flexible.

  • Log into your online account or use the app to create a Price Alert. We'll get in touch straight away if there's a deal you won't want to miss. It doesn't take long, and it'll save you time searching for flight tickets from Panama City to RDU every day.

  • Tailor your trip with filters. Pick your departure and arrival times, airlines and total journey duration. You can also sort results by 'Fastest,' 'Best' or 'Cheapest' flights from Panama City to Raleigh-Durham International Airport.

The best time to fly from Panama City to Raleigh-Durham International Airport (RDU)

  • It's time to work out your trip dates for your flight from Panama City to Raleigh-Durham International Airport. July is the most popular month to visit Durham. If you prefer a more relaxed vibe, go in May.

  • Book your flight from Panama City to RDU for July if you're eager to explore the city during its warmest month. You can expect temperatures in Durham to range from 19ºC to 33ºC.

  • If you want cooler conditions, lock in a cheap flight from Panama City to Raleigh-Durham International Airport in January when temperatures average between -3ºC and 13ºC.

More about Durham

Complete your Durham trip with a car rental

  • Exit all those tabs and let us do the hard work for you. We've also got amazing deals on car rentals in Durham once you've booked your cheap flight from Panama City to Raleigh-Durham International Airport. Easily compare prices in one place and drive off with a bargain that fits your budget.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.