Cheap flights from Panama City to Chicago

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Flight deals from Panama City to Chicago

Looking for a cheap last-minute deal or the best round-trip flight from Panama City to Chicago? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Panama City to Chicago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Chicago flights are currently cheapest in September.

Direct flights from Panama City to Chicago

Alternative Panama City to Chicago routes

Looking for the cheapest, fastest or easiest route from Panama City to Chicago? You could fly into the following airports instead.

Panama City to Chicago: Flight information

The things to know before you go.
Cheapest flight foundC$616
Cheapest month to flyAugust
Average flight time5 hrs, 45 mins
Most popular airlineCopa
Average flights per week46

Finding cheap flights from Panama City to Chicago: Frequently asked questions

There are 4 airports in Chicago: Chicago Midway, Chicago O'Hare International, Chicago Dupage County, and Chicago Rockford.
The best price we found for a round-trip flight from Panama City to Chicago is C$616. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 45 minutes is the average flight time from Panama City to Chicago.
Copa, United and EVA Air fly direct from Panama City to Chicago.
There are 184 flights per week flying from Panama City to Chicago, as of July 2025.
The cheapest month to fly from Panama City to Chicago is usually August.
If you're flying from Panama City, the cheapest airport near Chicago is Chicago O'Hare International – which is 25.4 km away from the center of Chicago. We've found flights to this airport from C$616.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Chicago on Tuesday, August 26, 2025.
Yes – the average flight time is 5 hours and 45 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Chicago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Chicago is around 40 days in advance, so don’t leave your flight to the last minute.
In July, the average temperature is usually around 22°C. July is typically the warmest month in Chicago, when it usually averages around 26°C. You can expect the least rain in January. The coldest month is January, with temperatures averaging -8°C. The rainiest month is August.
The cheapest airline that flies to Chicago is Avianca, and the cheapest airline that flies to Chicago O'Hare International Airport is Copa.

Flying from Panama City to Chicago: what you need to know

  • Panama City has a couple of airports where you can kick off your travels. Check out your options for booking a flight from Panama City to Chicago flying out of Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB).

  • When working out where to arrive in Chicago, O'Hare International Airport (ORD) and Chicago Midway International Airport (MDW) are the chief entry points.

  • The average length of a direct Panama City to Chicago flight is 5 hours 45 minutes.

  • Panama City and Chicago are in the same timezone, UTC-5.

  • The busiest route for flights from Panama City to Chicago is from Tocumen International Airport (PTY) to O'Hare International Airport (ORD). Take your pick of 11 services every week between these two airports. If you'd like to be on your way as soon as possible, the earliest flight from PTY to ORD is the 07:33 Copa Airlines option. If you prefer travelling later, the last scheduled departure is at 18:45 with Copa Airlines.

  • For hassle-free travel, turn up at the airport two hours ahead of international flights and one hour before domestic departures. That way, you won't have to rush to catch your Panama City to Chicago flight.

  • During popular months like June, you'll want to get to the airport earlier. Plan to arrive two hours before domestic departures and four hours ahead of an international flight whenever you're travelling during a peak period in general.

How to find the cheapest flights from Panama City to Chicago

  • Book two months before flying. Pricing trends suggest that this is the ideal window for finding cheap Panama City to Chicago flights.

  • May is the best month for picking up an amazing deal on a plane ticket from Panama City to Chicago. If you'd like to travel during a different time of year, the 'Whole month' tool will give you the lowest prices for every month.

  • Locking in a cheap flight from Panama City to Chicago couldn't be easier with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know as soon as there's a better deal.

  • Find a cheap Panama City to Chicago flight with the help of our filters. Select your preferred departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

Flying from Panama City

Tocumen International Airport (PTY)

  • Set out from Tocumen International Airport (PTY) on a nonstop flight from Panama City to Chicago. From PTY, you can fly directly into O'Hare International Airport (ORD).

  • Keep an eye out for deals with Copa Airlines. This carrier offers direct Panama City to Chicago plane tickets out of PTY.

  • We make it easy to find a Panama City to Chicago flight with a stopover. To see the options departing from Tocumen International Airport, uncheck 'Direct flights only.' Then, pick a flight with a stop long enough to see the sights of the city of your choice. Some popular stopovers include:

    • Orlando International Airport (MCO)

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Raleigh-Durham International Airport (RDU)

  • PTY is around 18 kilometres from central Panama City. If you're catching a cab, ride-sharing or driving from the centre, it'll take 20 minutes or so to get there, depending on traffic. If you're taking public transport, expect the journey time to be around 1 hour 5 minutes.

  • Want a hassle-free start to your travels? Stay near Tocumen International Airport. Whether you're catching an early flight from Panama City to Chicago or just don't like being rushed, these hotels are the answer:

  • 86.03% of flights departing from Tocumen International Airport land at their destination on time. With its strong on-time performance, you're unlikely to be delayed when taking off from PTY.

Panama Pacifico Airport (BLB)

  • BLB is about 11 kilometres from central Panama City. It'll take you 20 minutes or so to reach the airport driving from the city centre.

  • Start your vacation sooner with an additional night away from home. Before catching your flight from Panama City to Chicago, take it easy in one of these hotels near Panama Pacifico Airport:

  • The majority of flights that depart Panama Pacifico Airport get to their destination as expected. It maintains a high on-time performance rate of 86.75%.

Arriving in Chicago

O'Hare International Airport (ORD)

  • The distance from O'Hare International Airport (ORD) to central Chicago is roughly 26 kilometres. It takes about 35 minutes to reach the centre driving.

  • If you're taking public transport, expect a journey time of about 55 minutes.

  • Book a hotel near ORD if you have a late flight from Panama City to Chicago. Check in to one of these accommodation options and avoid the hassle of a long transfer:

  • Say yes to new adventures by picking up an O'Hare International Airport rental car. Grab your wheels from Routes Car Rentals, Dollar or Budget and explore beyond Chicago's main sights.

  • For the lowest price, reserve your vehicle from O'Hare International Airport around four weeks ahead of your Panama City to Chicago flight.

  • The street address for ORD is 10000 West O'Hare.

Chicago Midway International Airport (MDW)

  • Chicago Midway International Airport (MDW) is around 14 kilometres from the centre of Chicago. Following your flight from Panama City to Chicago, it takes approximately 20 minutes to get to the heart of the city in a cab or ride-share.

  • If you're catching public transport, it'll take approximately 45 minutes.

  • Place the 'Do not disturb' sign on your door and rest at a hotel close to MDW. Here are a few options where you can put your feet up after your flight from Panama City to Chicago:

  • The quickest way to get to where you're going is with a Chicago Midway International Airport rental car. Grab your wheels from Dollar, Hertz or Budget and make a speedy getaway.

  • Get what you want, not just what's left over. Reserving your ride from MDW four weeks in advance often means better deals and a wider range of vehicles.

  • The address for Chicago Midway International Airport is 5700 South Cicero.

Chicago Rockford International Airport (RFD)

  • Step off your flight from Panama City to Chicago and travel to your hotel or jump right into sightseeing. The centre of Chicago is around 129 kilometres from Chicago Rockford International Airport (RFD) and typically takes 1 hour 25 minutes to reach by car.

  • The journey will take you about 4 hours 15 minutes using public transport.

  • Whether you're looking for a mini for a solo trip or a spacious SUV to fit a group of friends, you'll find the right Chicago Rockford International Airport rental car for you. Check out the types of wheels available from companies such as Budget, Alamo and National.

  • Booking at least a few weeks in advance of your flight from Panama City to Chicago is always smart. As well as better deals, you'll have a wider selection of vehicle makes and models at RFD.

  • The street address for Chicago Rockford International Airport is 2 Airport Cir.

Best time to go to Chicago

  • January is the quietest month for flights from Panama City to Chicago, while August is the most popular. Choose the best time to go to Chicago based on whether you prefer a laid-back vibe or a lively atmosphere.

  • Book a Panama City to Chicago ticket departing in July if you want to experience the city during its warmest month. Expect temperatures in Chicago to range from 15ºC (59ºF) to 29ºC (84ºF).

  • Look for cheap flights from Panama City to Chicago in January if you'd rather travel when it's cooler. Temperatures are at their lowest then, ranging between -12ºC (10ºF) and 3ºC (37ºF) on average.

More about Chicago

  • When it comes to searching for somewhere to lay your head, you'll find the top stays in Chicago right here. Check out these options after locking in your flight from Panama City to Chicago:

  • There are so many things to do and see in this city it can be tricky to know where to begin. Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier are leading attractions which should be on any good Chicago itinerary.

Explore more of United States

  • Chicago will leave a lasting impression, but there are so many other corners of United States just waiting to be discovered. About 451 kilometres south-east of Chicago, a visit to Columbus will keep your itinerary busy. Start with popular sights like Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.

  • Around 257 kilometres south-east of Chicago, Indianapolis is another essential stop in United States. Experience major highlights starting with The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.